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Vinpocetine

Also known as: ARGH-4405; Cavinton; Ceractin; Ethyl Apovincaminate; Vincaton; Vincanton

Description

Vinpocetine is a type of Smart Drug that is derived from the Seeds of the Common Periwinkle (Vinca major) plant.

Health Benefits of Vinpocetine

Aging Process
Vinpocetine significantly decreases the decline in the release of Dopamine that normally occurs in tandem with the progression of the Aging Process. research

Cardiovascular System
Vinpocetine (10 mg per day) improves the flexibility of Red Blood Cells and may thereby help to prevent Strokes (a reduction in the flexibility of Red Blood Cells is associated with an increased risk of Stroke). research
Vinpocetine improves Blood Circulation to the Brain and thereby prevents and alleviates Cerebral Insufficiency. research

Ears/Hearing
Vinpocetine improves impaired Hearing (Deafness) in many cases (e.g. in some cases of sudden hearing loss): research
 
-Vinpocetine is an effective treatment for many cases of Sensorineural Hearing Loss. research
Vinpocetine improves many Inner-Ear problems.
Vinpocetine alleviates the symptoms of Meniere’s Disease. research
Vinpocetine alleviates Tinnitus. research
Vinpocetine alleviates Vertigo (dizziness) in 77% of patients.

Eyes/Vision
Vinpocetine improves the condition of Age-Related Macular Degeneration (ARMD) patients (primarily by improving Blood Circulation to the Eyes). research
Vinpocetine improves Blood Circulation to the Eyes (especially to the Retina and Macula regions). research
Vinpocetine helps to stabilize the condition of Glaucoma patients. research
Vinpocetine improves Sight in many people afflicted with Eyesight Disorders (especially where impaired Sight occurs as a result of sub-optimal Blood Circulation to the Eyes). research

Metabolism
Vinpocetine prolongs survival during periods of Anoxia (i.e. during the total absence of Oxygen). research
Vinpocetine possesses Antioxidant properties (it is comparable to Vitamin E in terms of its Antioxidant potential): research
 
-Vinpocetine deactivates Hydroxyl Free Radicals. research
Vinpocetine alleviates Fatigue (where the underlying cause of Fatigue is Cerebral Insufficiency). research

Nervous System
Vinpocetine increases the production of Adenosine Triphosphate (ATP) within the Brain's Neurons.
Vinpocetine increases Alertness (by improving Glucose and Oxygen utilization in the Brain). research
Vinpocetine may prevent and help to treat Alzheimer’s Disease.
Vinpocetine helps to prevent Amnesia (by improving Blood Circulation and Oxygen delivery to the Brain). research
Vinpocetine reduces Anxiety (where Anxiety is caused by Cerebral Insufficiency). research
Vinpocetine improves Blood Circulation within the Brain (i.e. it alleviates Cerebral Insufficiency by selectively dilating the Arteries of the Brain (the Cerebral Arteries)) and alleviates many of the side-effects (especially Mental Function) of people affected by Cerebral Insufficiency. research
Vinpocetine improves the function of the Noradrenergic Neurons located in the Brain Stem. research
Vinpocetine reduces Confusion (especially in people affected by Cerebral Insufficiency). research
Vinpocetine prevents and treats Multiple Infarct Dementia. research
Vinpocetine (10 mg per day) alleviates Depression in 74% of cases (especially where the underlying cause of Depression is Dementia or Cerebral Insufficiency). research
Vinpocetine reduces excessive Fear (where excessive Fear is caused by Cerebral Insufficiency). research
Vinpocetine alleviates Headaches in 78% of patients.
Vinpocetine enhances the function of the Hippocampus: research
 
-Vinpocetine enhances the function of the Dentate Gyrus region of the Hippocampus. research
Vinpocetine improves the Brain's utilization of Oxygen and increases the resistance of Neurons to the damage that would otherwise be caused by Hypoxia (i.e. it increases the Brain’s tolerance to Hypoxia and promotes Oxygen transport into Brain tissue). research
Vinpocetine accelerates the rate of Learning by up to 40%. research
Vinpocetine improves the function of and increases the activity of the Noradrenergic Neurons located in the Locus Coeruleus (a region within the Brain Stem). research
Vinpocetine improves Memory in normal, healthy people: research
 
-Healthy subjects exhibit significant Short-Term Memory improvement in as little as one hour after taking 40 mg of Vinpocetine. research
-Vinpocetine increases the length of time that Short-Term-Memory is retained.
-Vinpocetine blocks the action of other drugs that disrupt Memory.
Vinpocetine improves Long-Term Memory. research
Vinpocetine protects Neurons from damage and may reverse some aspects of Neuron damage (due to the Antioxidant properties of Vinpocetine). research
Vinpocetine alleviates Speech Impairment in 55% of cases.
Vinpocetine prevents and treats Stroke (by improving the Brain’s use of Oxygen). research
Vinpocetine (20 - 40 mg per day for short term use only) alleviates Vertigo in some people. research

Sleep Disorders
Vinpocetine alleviates several types of Sleep disorders:
 
-Vinpocetine alleviates Insomnia.

Sexual System (female)
The side-effects of Female Menopause respond well to Vinpocetine. research

Vinpocetine Enhances the Function of these Substances

Carbohydrates
Vinpocetine increases the Brain’s utilization of Glucose: research
 
-Vinpocetine shifts Glucose metabolism towards the more favorable aerobic pathway.
Vinpocetine protects Hyaluronic Acid from damage (due to the Antioxidant effects of Vinpocetine). research

Elements
Vinpocetine enhances the Brain’s utilization of Oxygen. research

Neurotransmitters
Vinpocetine significantly decreases the decline in the release of Dopamine that normally occurs in tandem with the progression of the Aging Process. research
Vinpocetine increases the Brain's turnover of Norepinephrine research
Vinpocetine increases the Brain's turnover of Serotonin.

Nucleic Compounds
Vinpocetine increases the Brain’s production of Adenosine Triphosphate (ATP). research

Proteins
Vinpocetine (15 mg per day) enhances the release of Oxygen from Hemoglobin. research

Vinpocetine Counteracts these Potentially Toxic Substances

Amino Acids
Vinpocetine helps to prevent damage to Neurons caused by exposure to excessive levels of Glutamic Acid (due to the Antioxidant properties of Vinpocetine). research

Side-Effects of Vinpocetine

Vinpocetine has no adverse interactions with other Smart Drugs or Pharmaceutical Drugs and the following side effects occur in only 1% of Vinpocetine users.

Cardiovascular System
Vinpocetine occasionally causes (transient) Hypotension (lowered Blood Pressure).
Vinpocetine can (rarely) cause (transient) Tachycardia.

Oral Health
Vinpocetine can (rarely) cause Dry Mouth.

Contraindications

Cardiovascular System
People who are prone to Hypotension (low Blood Pressure) should reduce the recommended dosage and monitor their Blood Pressure whilst using Vinpocetine.

Sexual System
Vinpocetine should not be used by women during Pregnancy.

Vinpocetine Compared with Vincamine

Vinpocetine is very similar to the related Smart Drug, Vincamine. In fact, Vinpocetine is derived from Vincamine. Vinpocetine is more potent and more effective than Vincamine.
Vinpocetine is at least two times (and in some cases, up to four times) more potent than Vincamine for most therapeutic purposes.

Safety Comparison
Vinpocetine causes Hypotension less frequently than Vincamine.
Vinpocetine causes Dry Mouth less frequently than Vincamine.

Dosage Recommendations

Healthy People
The recommended dosage of Vinpocetine for healthy people is 5 - 10 mg per day:
 
  1. When Vinpocetine is first used a “kickstart” dose of 15 - 30 mg should be used for one day.
Although the recommended dosage of Vinpocetine for healthy people is lower, clinical trials have demonstrated that maximum Memory improvement in healthy people occurs at a daily dosage of 40 mg of Vinpocetine.

Alzheimer’s Disease
The therapeutic, experimental dosage of Vinpocetine for Alzheimer’s Disease patients is 10 - 20 mg (average 15 mg) per day:
 
  1. When Vinpocetine is first used a “kickstart” dose of 30 mg should be used for one day.

Vertigo
The therapeutic, experimental dosage of Vinpocetine for Vertigo patients is 20 - 40 mg per day:
 
  1. This is a temporary dosage for Vinpocetine until the symptoms of Vertigo have subsided.

“Waiting Period”
The therapeutic effects of Vinpocetine begin to manifest after two days of Vinpocetine use.
The full therapeutic benefits of Vinpocetine are often not derived until it has been used on a daily basis for 12 months.

Commercial Availability of Vinpocetine

Oral Products
Vinpocetine is available from some health food stores and mail order supplement companies (only in the USA) in the form of 5 mg capsules (combined with 375 mg Arginine and 180 mg Vitamin C).
Vinpocetine is available from some international mail order pharmacies in the form of 5 mg tablets.

Chemical Data

Chemical Names
Eburnamenine-14-carboxylic acid ethylester
Ethyl-apovincaminate
3a, 16 a - apovincaminic acid-ethyl-ester

Molecular Formula
C22H26N2O2


Related Topics

Periwinkle Derivatives
Vincamine


Return Noradrenergic Neurons

Noradrenergic Neurons are Neurons that transmit the Neurotransmitter, Norepinephrine.